硫糖铝
Al8(OH)16(C12H14O35S8) [Al(OH)3]x [H2O]y
Sucralfate is the basic aluminium salt of sucrose octasulfate (SOS). The therapeutic effect of Sucralfate in gastric complaints is based on an increase in the protective mechanisms of the mucous membranes in the stomach and duodenum against exogenous and endogenous aggressors.
The cytoprotective action of Sucralfate includes the neutralization of acid, the selective formation of a protective layer over eroded surface areas, specific protection of lesions and adsorption of pepsin and bile acids, resulting in inhibition of peptic activity.
Sucralfate Powder S 215, S 225 and S 235
硫糖铝 S 215 粉末适用于片剂配方。硫糖铝 S225 是一种研磨粉末，适用于软片剂和糖果配方，或用于重悬的粉末混合物（粉末包）。硫糖铝 S 235 可用于直接可压缩片剂配方。
| 类型 | S 215 | S 225 | S 235 |
| Assay Al | 15,5 - 18,5 [%] | 15,5 - 18,5 [%] | 15,5 - 18,5 [%] |
| Assay SOS | 30,0 - 38,0 [%] | 30,0 - 38,0 [%] | 30,0 - 38,0 [%] |
| Density (tapped) | 0,55 - 0,75 [g/ml] | 0,30 - 0,48 [g/ml] | 0,6 - 0,8 [g/ml] |
| d50 | 30 - 70 [µm] | 3 - 5 [µm] | 90 - 130 [µm] |
| Pharmacopoeia | USP, PhEur | USP, PhEur | USP, PhEur |
Sucralfate Suspension
硫糖钠 S 611 和 S625 是活性含量为 30% 的悬浮液，用 p- 和 m-酯暂时保存。S611 适用于液体抗酸制剂，而 S625 是一种非常细的悬浮液，具有精细粒径。
Sucralfate Suspension S601 is used in medical devices and is temporarily preserved with hydrogen peroxide.
凭借我们对硫硫酸盐的深入了解和对散装产品的生产授权，我们能够生产硫硫酸盐最终产品。Together with our long-term partners we can thus offer full service for Sucralfate suspensions.
| 类型 | S601 | S611 | S625 |
| Assay | > 4,8 [%] | 4,7 - 6,0 [%] | 4,7 - 6,0 [%] |
| Assay SOS | > 8,6 [%] | 8,3 - 13,4 [%] | 9,1 - 12,3 [%] |
| Particle size | d50: 5 - 10 µm | d50: 5 - 10 µm | d50: 3 - 5 µm min 85% < 10 µm |
| Pharmacopoeia | USP | USP |
